Mistletoe - From Mythology to Evidence-Based Medicine
نویسنده
چکیده
This is the time of the precision medicine, as President Barak Obama addressed the Nation on January 20, 2015 in a State of the Union Address: Tonight, I'm launching a new Precision Medicine Initiative to bring us closer to curing diseases like cancer and diabetes - and to give all of us access to the personalized information we need to keep ourselves and our families healthier (Francis S. Collins and Harold Varmus, A New Initiative on Precision Medicine; N Engl J Med 2015;372:793-795). This new field already show several actors, not only the NIH but also private company like APPLE, MICROSOFT and others, investing a lot of many: all together already several billions, dollars or euro doesn't matter, a fact that testify how hot is becoming this new biomedical perspective....
منابع مشابه
Difficulties and Perspectives of Immunomodulatory Therapy with Mistletoe Lectins and Standardized Mistletoe Extracts in Evidence-Based Medicine
Viscum album preparations are aqueous mistletoe plant extracts used in complementary and alternative medicine as immunomodulators in cancer therapy. However, evidence of immunological efficacy of mistletoe extracts (MEs) used in clinical trials is often lacking. Mechanisms involved in anti-tumor properties of ME and mistletoe lectins (MLs) modify both innate and adaptive immune systems, accordi...
متن کاملOncopharmacological Perspectives of a Plant Lectin (Viscum album Agglutinin-I): Overview of Recent Results from In vitro Experiments and In vivo Animal Models, and Their Possible Relevance for Clinical Applications
An old goal of natural complementary medical therapy has been to aim at a long-term stimulation of natural resistance in order to restrain cancer progression or improve defective immunological conditions without toxic side effects. Mistletoe extracts were applied to a large number of cancer patients because of their modulatory effect on the natural immune system. By carefully removing lectins, ...
متن کاملDrying Methods Alter Angiotensin-I Converting Enzyme Inhibitory Activity, Antioxidant Properties, and Phenolic Constituents of African Mistletoe (Loranthus bengwensis L) Leaves.
This study investigated the most appropriate drying method (sun drying, oven drying, or air drying) for mistletoe leaves obtained from almond tree. The phenolic constituents were characterized using high-performance liquid chromatography-diode array detector, while the inhibitory effect of the aqueous extracts of the leaves on angiotensin-I converting enzyme (ACE) was determined in vitro as als...
متن کاملCorrelation between the Eponyms of Medical Sciences and Mythology
The medical terms currently used are derived from a variety of sources. These terms are often derived from an eponym. Eponyms are a long-standing tradition in medicine. Eponyms usually involve honoring a prominent physician-scientist who played a significant role in identifying the disease or the person who first reported the disease or the area where a disease first broke out in there. Eponyms...
متن کاملSafety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study
Background. Traditional mistletoe therapy in cancer patients involves subcutaneous applications of Viscum album L. preparations, with doses slowly increasing based on patient responses. Intravenous infusion of high doses may improve therapeutic outcomes and is becoming more common. Little is known about the safety of this "off-label" application of mistletoe. Methods. An observational study was...
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